Search on: CATHEPSIN C 
Descriptors Found: 1
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Descriptor English:   Cathepsin C 
Descriptor Spanish:   Catepsina C 
Descriptor Portuguese:   Catepsina C 
Synonyms English:   Dipeptidyl Peptidase I
Dipeptidyl Aminopeptidase I  
Tree Number:   D08.811.277.656.224.130
D08.811.277.656.262.186
D08.811.277.656.350.350.100
Definition English:   A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE. 
History Note English:   2010(1981) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   34436 
Unique Identifier:   D020789 

Occurrence in VHL: 		 

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